wound healing and toxicity evaluation of aloe vera cream on outpatients with second degree burns

aloe vera is a tropical plant belonging to the liliaceae family. it has beneficialeffects in variety of diseases. the aim of this study was to formulate a topical cream from a. vera with wound burn healing effect and to perform its clinical trial. a total of 30 patients (20 males and 10 females in the age range of 20-50 years) with second degree burn wounds on their both hands were selected for the study. the subjects used a. vera topical formulation or silver sulfadiazine 1% cream on each hand as the test and control, symmetrically. the rate of healing was measured and compared on 0 to 18 days after treatment. results indicated that average percent of healing with a. vera on day 10 was 90.6% compared with silver sulfadiazine which was only 29.8% (pa. vera on burn wounds without any adverse dermal toxic effects is very promisingand it may be employed in management of burn wound, routinely.